6-(Trifluoromethyl)quinoline-3-carboxylic acid CAS 71082-45-6
| CAS No. | 71082-45-6 |
| Molecular Formula | C11H6F3NO2 |
| Molecular Weight | 241.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-(Trifluoromethyl)quinoline-3-carboxylic acid (CAS 71082-45-6), a certified reference material (molecular formula C11H6F3NO2, MW 241.17 g/mol) for analytical method development and quality control.
Based on its molecular formula C11H6F3NO2, 6-(Trifluoromethyl)quinoline-3-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 241.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 6-(Trifluoromethyl)quinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6F3NO2 |
| Molecular Weight | 241.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 8-(Trifluoromethyl)quinoline-2-carboxylic acid (CAS 1023815-99-7)
- 6-(Trifluoromethyl)quinoline-4-carboxylic acid (CAS 1092288-36-2)
- 7-(Trifluoromethyl)quinoline-2-carboxylic acid (CAS 1092304-95-4)
- 1-(3-(Trifluoromethyl)phenyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 113934-28-4)
- 2-(4-(Trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carbaldehyde (CAS 1202942-42-4)
- 7-(Trifluoromethyl)isoquinoline-3-carboxylic acid (CAS 1256787-80-0)
- 3-Phenyl-4-(trifluoromethyl)isoxazole-5-carbaldehyde (CAS 1260663-50-0)
- 2-(Trifluoromethyl)quinoline-5-carboxylic acid (CAS 1260671-21-3)
Recommended Standards
- 6-(Trifluoromethyl)quinoline-2-carboxylic acid (CAS 849818-58-2)
- 6-(Trifluoromethyl)quinoline-8-carboxylic acid (CAS 2089649-11-4)
- 6-(Trifluoromethyl)isoquinoline-4-carboxylic acid (CAS 2177266-08-7)
- 7-(Trifluoromethyl)quinoline-3-carboxylic Acid (CAS 71082-51-4)
- 4-(3-bromo-4-fluorophenoxy)benzene-1-sulfonyl chloride (CAS 1551735-52-4)
- (R)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-1-ol (CAS 2505078-37-3)
- N-(4-((3-(4-Bromophenyl)thioureido)methyl)phenyl)acetamide (CAS 403830-56-8)
- 1,8-Dichloro-10-methylanthracene (CAS 17122-95-1)
- 4-Methoxy-2-methylbenzohydrazide (CAS 75319-01-6)
- Argatroban Impurity 51 (CAS CATO-C4X-100751)
- Epinastine Impurity 49 (CAS 2831006-70-1)
- 3-Hydroxy-8-methylbenzo[d][1,2,3]triazin-4(3H)-one (CAS 1818447-60-7)
- 2,3-Bis(4-hydroxyphenyl)cycloprop-2-enone (CAS 25361-95-9)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
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