5-(5-Nitrofuran-2-yl)-1,3,4-thiadiazol-2-amine CAS 712-68-5
| CAS No. | 712-68-5 |
| Molecular Formula | C6H4N4O3S |
| Molecular Weight | 212.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(5-Nitrofuran-2-yl)-1,3,4-thiadiazol-2-amine (CAS 712-68-5) is a high-purity analytical reference standard with the molecular formula C6H4N4O3S and a molecular weight of 212.19 g/mol.
The molecular framework of 5-(5-Nitrofuran-2-yl)-1,3,4-thiadiazol-2-amine (C6H4N4O3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-(5-Nitrofuran-2-yl)-1,3,4-thiadiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4N4O3S |
| Molecular Weight | 212.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Nitrofuran Standards
- 5-(5-Nitrofuran-2-yl)-1H-1,2,4-triazole-3(2H)-thione (CAS 57672-16-9)
- 1-Methyl-2-((5-nitrofuran-2-yl)methylene)hydrazinecarboxamide (CAS 6281-25-0)
- 5-Nitrofuran-2-sulfonyl chloride (CAS 98026-86-9)
- 5-(5-Nitrofuran-2-yl)-1,3,4-oxadiazole-2(3H)-thione (CAS 94646-96-5)
- 4-Methyl-2-(5-nitrofuran-2-yl)-1,3-dioxane (CAS 51792-29-1)
- Butyl 5-nitrofuran-2-carboxylate (CAS 20001-38-1)
- Ethyl 3-(5-nitrofuran-2-yl)acrylate (CAS 93303-56-1)
- 2-[(5-nitrofuran-2-yl)formamido]acetic acid (CAS 52980-52-6)
Recommended Standards
- 4-(4-(Difluoromethoxy)phenyl)but-3-en-2-one (CAS 392290-56-1)
- 3-(Trifluoroacetyl)tetrahydrothiopyran-4-one (CAS 2064-82-6)
- Ethyl (E)-3-(2,5-difluorophenyl)acrylate (CAS 881658-90-8)
- 2-Amino-5-(dimethylphosphoryl)benzamide (CAS 2903924-55-8)
- 1,5-Dichloroanthraquinone (CAS 82-46-2)
- rac-(3R,4R)-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1909288-72-7)
- 5-(4-Methoxyphenyl)oxazol-2(3H)-one (CAS 2566696-23-7)
- Raltitrexed Impurity 15 (CAS CATO-C4X-138615)
- Benzofuran-6-ylmethanol (CAS 1056942-24-5)
- Pyronaridine Impurity 3 (CAS CATO-C4X-29783)
- Z77H3IKW94 7784-18-1 Aluminum fluoride Aluminium fluoride Aluminum fluoride (AlF3) Aluminium fluorure [French] Aluminum trifluoride CCRIS 2282 EINECS 232-051-1 Fluorid hlinity [Czech] HSDB 600 Aluminium fluorure Fluorid hlinity UNII-Z77H3IKW94 EC 232-051-1 (CAS 7784-18-1)
- 2-Ethyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1218789-94-6)
- 3,5,7-Trihydroxy-8-(3-methylbut-2-en-1-yl)-2-phenyl-4H-chromen-4-one (CAS 42193-83-9)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com