Ethyl 2-(4-chlorophenyl)quinoline-4-carboxylate CAS 7147-98-0
| CAS No. | 7147-98-0 |
| Molecular Formula | C18H14ClNO2 |
| Molecular Weight | 311.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-(4-chlorophenyl)quinoline-4-carboxylate.
Ethyl 2-(4-chlorophenyl)quinoline-4-carboxylate (CAS 7147-98-0) is a high-purity analytical reference standard with the molecular formula C18H14ClNO2 and a molecular weight of 311.76 g/mol.
The molecular framework of Ethyl 2-(4-chlorophenyl)quinoline-4-carboxylate (C18H14ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-(4-chlorophenyl)quinoline-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO2 |
| Molecular Weight | 311.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(2-Chlorophenyl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 587850-79-1)
- 2-(2-Chlorophenyl)-6-ethylquinoline-4-carboxylic acid (CAS 667435-73-6)
- 2-(2-Chlorophenyl)-7,8-dimethylquinoline-4-carboxylic acid (CAS 667435-72-5)
- 2-(2-Chlorophenyl)-8-ethylquinoline-4-carboxylic acid (CAS 667435-74-7)
- 2-(3-Chlorophenyl)-3,6-dimethylquinoline-4-carboxylic acid (CAS 438216-04-7)
- 2-(3-Chlorophenyl)-3,8-dimethylquinoline-4-carboxylic acid (CAS 932929-06-1)
- 2-(4-Chlorophenyl)-3,6-dimethylquinoline-4-carboxylic acid (CAS 438217-37-9)
- 2-(4-Chlorophenyl)-3,8-dimethylquinoline-4-carboxylic acid (CAS 492448-66-5)
Recommended Standards
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- Ethyl 1-(2-chlorophenyl)isoquinoline-3-carboxylate (CAS 89242-07-9)
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- Methyl 2-amino-4-(2-chlorophenyl)thiazole-5-carboxylate (CAS 1065074-40-9)
- Oxocan-4-yl acetate (CAS 38786-82-2)
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- Methyl 5-bromo-2-ureidothiophene-3-carboxylate (CAS 845889-21-6)
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- 2-(5-(2-Hydroxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazole-1-carbonyl)benzoic acid (CAS 353763-50-5)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
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