4-(4-Nitro-1,3-dioxoisoindolin-2-yl)benzoic acid CAS 71494-65-0
| CAS No. | 71494-65-0 |
| Molecular Formula | C15H8N2O6 |
| Molecular Weight | 312.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Nitro-1,3-dioxoisoindolin-2-yl)benzoic acid (C15H8N2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(4-Nitro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 71494-65-0) is a high-purity analytical reference standard with the molecular formula C15H8N2O6 and a molecular weight of 312.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H8N2O6 |
| Molecular Weight | 312.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 2 |
Related Nitro Standards
- 2-(4-Nitro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 100914-35-0)
- 3-(4-Nitro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 300405-52-1)
- 2-Nitro-5-(((4-nitrophenyl)sulfonyl)methyl)furan (CAS 61266-29-3)
- 2-Nitro-4-(3-(trifluoromethyl)pyridin-2-yl)benzoic acid (CAS 573676-07-0)
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