Dacarbazine Impurity 2 CAS 7151-03-3
| CAS No. | 7151-03-3 |
| Molecular Formula | C4H3N5O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Dacarbazine Impurity 2 (CAS 7151-03-3, C4H3N5OH2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Dacarbazine Impurity 2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 155.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Dacarbazine Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H3N5O H2O |
| Molecular Weight | 155.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 5 |
Related Dacarbazine Standards
- Dacarbazine-d6 (N,N-dimethyl-d6) (CAS 1185241-28-4)
- Dacarbazine EP Impurity C (CAS 1314929-56-0)
- Dacarbazine (CAS 4342-03-4)
- Dacarbazine EP Impurity A (CAS 4656-86-4)
- Dacarbazine Impurity 3 (CAS 506-59-2)
- Dacarbazine Impurity 1 (CAS 63907-29-9)
- Dacarbazine EP Impurity B HCl (CAS 72-40-2)
- Dacarbazine Lactose Adduct Impurity (CAS CATO-C4X-23054)
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