Dacarbazine EP Impurity B HCl CAS 72-40-2
| CAS No. | 72-40-2 |
| Molecular Formula | C4H6N4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 162.58 g/mol gives Dacarbazine EP Impurity B HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Dacarbazine EP Impurity B HCl (CAS 72-40-2) is a certified pharmaceutical impurity reference standard with the molecular formula C4H6N4OHCl and a molecular weight of 162.58 g/mol.
Dacarbazine EP Impurity B HCl (C4H6N4OHCl) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dacarbazine EP Impurity B HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H6N4O HCl |
| Molecular Weight | 162.58 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dacarbazine Standards
- Dacarbazine-d6 (N,N-dimethyl-d6) (CAS 1185241-28-4)
- Dacarbazine EP Impurity C (CAS 1314929-56-0)
- Dacarbazine (CAS 4342-03-4)
- Dacarbazine EP Impurity A (CAS 4656-86-4)
- Dacarbazine Impurity 3 (CAS 506-59-2)
- Dacarbazine Impurity 1 (CAS 63907-29-9)
- Dacarbazine Impurity 2 (CAS 7151-03-3)
- Dacarbazine Lactose Adduct Impurity (CAS CATO-C4X-23054)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com