(2S)-4-Hydroxy-5-oxopyrrolidine-2-carboxylic acid CAS 716361-98-7
| CAS No. | 716361-98-7 |
| Molecular Formula | C5H7NO4 |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2S)-4-Hydroxy-5-oxopyrrolidine-2-carboxylic acid.
(2S)-4-Hydroxy-5-oxopyrrolidine-2-carboxylic acid (CAS 716361-98-7), molecular formula C5H7NO4 and molecular weight 145.11 g/mol, is a CATO reference standard with documented purity and traceability.
(2S)-4-Hydroxy-5-oxopyrrolidine-2-carboxylic acid (C5H7NO4) contains a carbohydrate-derived structure, an amide group. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7NO4 |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related S Standards
- Methyl 5-hydroxy-4,5-dihydroisoxazole-3-carboxylate (CAS 170648-38-1)
- (S)-1-Hydroxy-5-oxopyrrolidine-2-carboxylic acid (CAS 760174-11-6)
- Trans-3-hydroxy-5-oxopyrrolidine-2-carboxylic acid (CAS 24135-75-9)
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Recommended Standards
- O-(3,5-difluorophenyl)hydroxylamine (CAS 197588-25-3)
- (3,5-Difluoropyridin-4-yl)methanol (CAS 924649-16-1)
- 6,6-difluoro-2-oxabicyclo[3.1.0]hexane-1-carbonitrile (CAS 1955557-96-6)
- (4S,5S)-5-Methyl-2-oxooxazolidine-4-carboxylic acid (CAS 98302-45-5)
- 4-Chloro-6-(4'-trifluoromethylphenyl)pyrimidine (CAS 659729-09-6)
- 2-(1,2,4-Oxadiazol-3-yl)ethan-1-amine hydrochloride (CAS 1315365-77-5)
- 2,7-Dimethyloctahydroquinolin-4(1H)-one (CAS 60141-43-7)
- 6-Bromo-2-chloro-7-nitroquinoline (CAS 1269151-42-9)
- 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-pyrrol-2-yl)propanoic acid (CAS 1379859-26-3)
- methyl 4-bromo-1H-imidazole-2-carboxylate (CAS 1622843-37-1)
- 1-(4-Ethylphenyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1490663-53-0)
- 2-Nitro-2-phenylpropane-1,3-diol (CAS 5428-02-4)
- Methyl 2-(2-ethoxy-2-oxoethoxy)quinoline-4-carboxylate (CAS 2007916-54-1)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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