O-(3,5-difluorophenyl)hydroxylamine CAS 197588-25-3
| CAS No. | 197588-25-3 |
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
O-(3,5-difluorophenyl)hydroxylamine (C6H5F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
O-(3,5-difluorophenyl)hydroxylamine (CAS 197588-25-3) is a high-purity analytical reference standard with the molecular formula C6H5F2NO and a molecular weight of 145.11 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related O Standards
- (3,5-Difluorophenyl)hydrazine (CAS 134993-88-7)
- (3,4-Difluorophenyl)hydrazine (CAS 161886-22-2)
- (2,4-difluorophenyl)hydrazine (CAS 40594-30-7)
- (2,4-Difluorophenyl)methanol (CAS 56456-47-4)
- (2,5-Difluorophenyl)methanol (CAS 75853-20-2)
- (2,3-Difluorophenyl)methanamine (CAS 72235-51-9)
- (2,5-Difluorophenyl)methanamine (CAS 85118-06-5)
- (3,5-Difluorophenyl)methanamine hydrochloride (CAS 90389-28-9)
Recommended Standards
- 6,6-difluoro-2-oxabicyclo[3.1.0]hexane-1-carbonitrile (CAS 1955557-96-6)
- (2S)-4-Hydroxy-5-oxopyrrolidine-2-carboxylic acid (CAS 716361-98-7)
- 6-(Difluoromethyl)pyridin-2(1H)-one (CAS 195044-11-2)
- (3,5-Difluoropyridin-4-yl)methanol (CAS 924649-16-1)
- 2-(5-(Azepan-1-ylmethyl)-1H-tetrazol-1-yl)acetic acid hydrochloride (CAS 1119449-90-9)
- Ethyl 4-amino-5-bromonicotinate (CAS 1240595-43-0)
- (2S,6S)-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester (CAS 1268816-80-3)
- Cabozantinib Impurity 41 (CAS 2105956-20-3)
- 4-((2-(Cyclohex-2-en-1-yl)ethyl)amino)butan-1-ol (CAS 923526-83-4)
- Ethyl 2-bromo-2-(3-fluorophenyl)acetate (CAS 66504-00-5)
- Sepiapterin impurity 14 (CAS CATO-C4X-276614)
- 4-Fluoro-3-isopropoxy-5-methylbenzaldehyde (CAS 2484889-03-2)
- o1-Tert-butylo3-methyl(3S)-3-methylpyrrolidine-1,3-dicarboxylate (CAS 2375165-13-0)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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