2’-Chloro-5’-(trifluoromethyl)acetophenone CAS 71648-45-8
| CAS No. | 71648-45-8 |
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2’-Chloro-5’-(trifluoromethyl)acetophenone (CAS 71648-45-8), a certified reference material (molecular formula C9H6ClF3O, MW 222.59 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H6ClF3O, 2’-Chloro-5’-(trifluoromethyl)acetophenone contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 222.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2’-Chloro-5’-(trifluoromethyl)acetophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF3O |
| Molecular Weight | 222.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-2-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1023812-01-2)
- 1-(5-Chloro-2-(trifluoromethyl)phenyl)ethan-1-one (CAS 1214362-82-9)
- 1-(3-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-21-6)
- 1-(5-Chloro-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1256467-25-0)
- 4-Chloro-6-(trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-c]pyridine (CAS 1260666-44-1)
- 1-[3-chloro-4-(trifluoromethyl)phenyl]ethan-1-one (CAS 129322-80-1)
- 2’-Chloro-4’-(trifluoromethyl)acetophenone (CAS 129322-81-2)
- 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 129322-82-3)
Recommended Standards
- 2',4'-Dichloro-2,2,2-trifluoroacetophenone (CAS 898787-49-0)
- 2-Chloro-1-(2-(trifluoromethyl)phenyl)ethan-1-one (CAS 914206-35-2)
- 2-(3-Chloro-4-(trifluoromethyl)phenyl)acetaldehyde (CAS 2228973-02-0)
- 2-chloro-1-[3-(trifluoromethyl)phenyl]ethan-1-one (CAS 439807-20-2)
- (2Z)-2-Cyano-N-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]-3-phenylprop-2-enamide (CAS 338976-66-2)
- 3-Methoxycyclopentane-1-carboxylic acid (CAS 102539-67-3)
- Disperse Blue 102 (CAS 12222-97-8)
- Ethyl 4-amino-3-(3-chloro-4-fluorophenyl)-2-thioxo-2,3-dihydrothiazole-5-carboxylate (CAS 312922-20-6)
- 2-Bromo-N-(1,3,4-thiadiazol-2-yl)benzamide (CAS 303794-76-5)
- 4-Mercapto-6,7-dimethoxyquinoline-3-carbonitrile (CAS 1458088-81-7)
- Tert-butyl 2-amino-3-bromobenzoate (CAS 1343490-67-4)
- Neodymium 145 (CAS 14336-84-6)
- Furan-2-yl(5-methylfuran-2-yl)methanol (CAS 356552-27-7)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com