2',4'-Dichloro-2,2,2-trifluoroacetophenone CAS 898787-49-0

Description

Compared with other compounds in its class, the molecular weight of 222.59 g/mol gives 2',4'-Dichloro-2,2,2-trifluoroacetophenone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2',4'-Dichloro-2,2,2-trifluoroacetophenone (CAS 898787-49-0), molecular formula C9H6ClF3O and molecular weight 222.59 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2',4'-Dichloro-2,2,2-trifluoroacetophenone (C9H6ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2',4'-Dichloro-2,2,2-trifluoroacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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