4-(3-Chloro-4-fluorophenyl)benzaldehyde CAS 718628-28-5
| CAS No. | 718628-28-5 |
| Molecular Formula | C13H8ClFO |
| Molecular Weight | 234.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3-Chloro-4-fluorophenyl)benzaldehyde.
4-(3-Chloro-4-fluorophenyl)benzaldehyde (CAS 718628-28-5), molecular formula C13H8ClFO and molecular weight 234.65 g/mol, is a CATO reference standard with documented purity and traceability.
4-(3-Chloro-4-fluorophenyl)benzaldehyde (C13H8ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(3-Chloro-4-fluorophenyl)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8ClFO |
| Molecular Weight | 234.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3'-Chloro-4'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1181381-74-7)
- 4-Chloro-2-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1214368-61-2)
- 5'-Chloro-2'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-22-5)
- 2'-Chloro-5'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-34-9)
- 2'-Chloro-4'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-55-4)
- 4'-Chloro-2'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-63-4)
- 3'-Chloro-2'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-77-0)
- 3'-Chloro-5'-fluoro-[1,1'-biphenyl]-3-carbaldehyde (CAS 1242339-78-1)
Recommended Standards
- 3-Chloro-3-fluorobenzophenone (CAS 75762-57-1)
- 4'-Chloro-3'-fluoro-[1,1'-biphenyl]-2-carbaldehyde (CAS 223575-82-4)
- 2-chloro-9-(1-methyl-1H-pyrazol-4-yl)-9H-purine (CAS 2386703-96-2)
- 4'-Chloro-3'-fluoro[1,1'-biphenyl]-4-carbaldehyde (CAS 842140-45-8)
- 1-(Dimethylamino)cyclopropanecarbaldehyde (CAS 1229114-92-4)
- 2-((tert-Butoxycarbonyl)amino)-4-(thiophen-2-yl)butanoic acid (CAS 1404826-32-9)
- H-D-Ala-Leu-OH (CAS 67113-60-4)
- 2,3,4-Trichloroquinoline (CAS 40335-02-2)
- (2R)-2-amino-3-(oxan-4-yl)propanoic acid hydrochloride (CAS 1207447-38-8)
- 2,2-Difluoro-3-(2-methyl-1H-indol-3-yl)propanoic acid (CAS 1889024-64-9)
- Z-Val-Phe-OH (CAS 19542-51-9)
- 3-Cyclopropoxy-4-methoxy-N,N-dimethylpyridin-2-amine (CAS 1243356-96-8)
- Z-Gly-Gly-Trp-OH (C-1800.0001) (CAS 83798-91-8)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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