Ranitidine EP Impurity H CAS 72078-82-1
| CAS No. | 72078-82-1 |
| Molecular Formula | C3H6N2O3 |
| Molecular Weight | 118.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 118.09 g/mol gives Ranitidine EP Impurity H distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ranitidine EP Impurity H (CAS 72078-82-1) is a certified pharmaceutical impurity reference standard with the molecular formula C3H6N2O3 and a molecular weight of 118.09 g/mol.
The molecular framework of Ranitidine EP Impurity H (C3H6N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ranitidine EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H6N2O3 |
| Molecular Weight | 118.09 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 2 |
Related Ranitidine Standards
- Ranitidine Impurity 14 (CAS 871-76-1)
- Ranitidine Impurity 13 (CAS 66357-40-2)
- Ranitidine Impurity 23 (CAS CATO-C4X-137023)
- Ranitidine Impurity N6 (CAS 1197-40-6)
- Ranitidine Impurity 11 (CAS 102721-76-6)
- Ranitidine Impurity N1 (CAS 15433-79-1)
- Ranitidine EP Impurity G (CAS 148639-72-9)
- Ranitidine Impurity 24 (CAS 13623-94-4)
Recommended Standards
- N-methyl-N-nitrosoglycine(Mixture of Isomers) (CAS 55332-68-8)
- Methylmalonic Acid (CAS 516-05-2)
- Oxalic Acid Ethyl Ester (CAS 617-37-8)
- Dimethyl oxalate (CAS 553-90-2)
- Eltrombopag Impurity 41 (CAS 17933-03-8)
- (7R)-Sitafloxacin Impurity 13 (CAS 127199-44-4)
- Dronedarone Impurity 13 (CAS 748763-03-3)
- N-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamothioyl)-2-phenylacetamide (CAS 313959-18-1)
- 1,6-Dimethylnaphthalen-2-ol (CAS 17324-10-6)
- 3-{[(4-tert-butylphenyl)methyl]amino}propanoic acid hydrochloride (CAS 1170629-15-8)
- 1-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 1244979-90-5)
- 2-(3-Isopropoxyphenyl)-2-oxoacetic acid (CAS 1443329-95-0)
- 2-(4-(2-Methoxyphenyl)-1H-1,2,3-triazol-1-yl)-2-methylpropanoic acid (CAS 2138531-35-6)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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