Ranitidine EP Impurity G CAS 148639-72-9

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.148639-72-9
Molecular FormulaC5H9N3OS
Molecular Weight159.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ranitidine EP Impurity G CAS 148639-72-9 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO supplies Ranitidine EP Impurity G (CAS 148639-72-9), a pharmacopoeial impurity reference standard (molecular formula C5H9N3OS, MW 159.21 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ranitidine EP Impurity G (C5H9N3OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), Ranitidine EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H9N3OS
Molecular Weight159.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1999
Nitrogen Atoms3
Sulfur Atoms1

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