8-Isoquinolinylboronic acid CAS 721401-43-0
| CAS No. | 721401-43-0 |
| Molecular Formula | C9H8BNO2 |
| Molecular Weight | 172.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Isoquinolinylboronic acid is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-Isoquinolinylboronic acid (CAS 721401-43-0), molecular formula C9H8BNO2 and molecular weight 172.98 g/mol, is a CATO reference standard with documented purity and traceability.
8-Isoquinolinylboronic acid (C9H8BNO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Isoquinolinylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8BNO2 |
| Molecular Weight | 172.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 6-Quinolineboronic Acid (CAS 376581-24-7)
- Isoquinolin-5-ylboronic acid (CAS 371766-08-4)
- 4-Quinolineboronic Acid (CAS 371764-64-6)
- Isoquinolin-6-ylboronic acid (CAS 899438-92-7)
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