2-[2-(4-Difluoromethoxy-phenyl)-2-oxo-ethylsulfanyl]-benzoic acid CAS 721406-30-0
| CAS No. | 721406-30-0 |
| Molecular Formula | C16H12F2O4S |
| Molecular Weight | 338.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[2-(4-Difluoromethoxy-phenyl)-2-oxo-ethylsulfanyl]-benzoic acid.
2-[2-(4-Difluoromethoxy-phenyl)-2-oxo-ethylsulfanyl]-benzoic acid (CAS 721406-30-0), molecular formula C16H12F2O4S and molecular weight 338.33 g/mol, is a CATO reference standard with documented purity and traceability.
2-[2-(4-Difluoromethoxy-phenyl)-2-oxo-ethylsulfanyl]-benzoic acid (C16H12F2O4S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[2-(4-Difluoromethoxy-phenyl)-2-oxo-ethylsulfanyl]-benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12F2O4S |
| Molecular Weight | 338.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
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Recommended Standards
- 2-((2-Ethoxyphenyl)sulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole (CAS 62617-22-5)
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- 1-Ethyl 4-(tert-Butyl) 2-(diethyl phosphono)succinate (CAS 77924-28-8)
- Ethyl 4-(((3-(4-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)amino)-4-oxobutanoate (CAS 954616-56-9)
- 4-(((3-(3-Ethyl-1-methylazepan-3-yl)phenoxy)carbonyl)amino)benzoic acid (CAS 1314003-47-8)
- (4-Butylphenyl)(pyridin-3-yl)methanone (CAS 61779-99-5)
- 4,7-Dibromo-1-ethyl-1H-benzo[d]imidazole (CAS 2365306-39-2)
- Ethyl 2-((4-(1-ethyl-3-methyl-1h-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl)sulfonyl)acetate (CAS 1006328-62-6)
- 3-(4-Methyl-2-piperidin-1-ylpyrimidin-5-yl)-1H-pyrazol-5-ol (CAS 1452577-04-6)
- Ethyl 7-(tert-butyl)-3-(4-nitrobenzoyl)indolizine-1-carboxylate (CAS 853329-83-6)
- 2-(Methylamino)-N-(1-phenylpropyl)propanamide (CAS 1247162-39-5)
- Ethyl 2-amino-4-fluoro-4-methylpentanoate (CAS 885498-60-2)
- Methyl 4-amino-6-chloro-5-fluoronicotinate (CAS 2621932-27-0)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
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