4-(3-Chlorophenyl)-5-[3-(morpholine-4-sulfonyl)phenyl]-4H-1,2,4-triazole-3-thiol CAS 721418-75-3
| CAS No. | 721418-75-3 |
| Molecular Formula | C18H17ClN4O3S2 |
| Molecular Weight | 436.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3-Chlorophenyl)-5-[3-(morpholine-4-sulfonyl)phenyl]-4H-1,2,4-triazole-3-thiol (CAS 721418-75-3) is a high-purity analytical reference standard with the molecular formula C18H17ClN4O3S2 and a molecular weight of 436.94 g/mol.
4-(3-Chlorophenyl)-5-[3-(morpholine-4-sulfonyl)phenyl]-4H-1,2,4-triazole-3-thiol (C18H17ClN4O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN4O3S2 |
| Molecular Weight | 436.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
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Recommended Standards
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- Losartan Impurity 19 (CAS 114798-94-6)
- Dapagliflozin Impurity 69 (CAS 3093141-55-7)
- Losartan impurity 31 (CAS CATO-C4X-168331)
- 4-(Bromomethyl)-2,3-dimethylpyridine (CAS 2090991-73-2)
- [3-(3-bromophenyl)-1,2,4-oxadiazol-5-yl]methanamine hydrochloride (CAS 1803566-73-5)
- (3-Chloro-4-fluorobenzyl)(3-fluorophenyl)sulfane (CAS 1443312-78-4)
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- Methylcis-3-hydroxy-3-phenyl-cyclobutanecarboxylate (CAS 69584-45-8)
- 149282-22-4 N'-(3,4-Dichlorophenyl)-N-[(4-fluorophenyl)methyl]-N-methoxyurea DTXSID60375706 (CAS 149282-22-4)
- 3-[3-(4-ethylphenyl)-1,2,4-oxadiazol-5-yl]propanoic acid (CAS 889946-88-7)
- Ethyl 4-fluoro-8-(2-oxo-1,2-dihydropyridin-3-yl)-6H-furo[2,3-e]indole-7-carboxylate (CAS 1037764-11-6)
- 2-[4,5-Dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-[(β-D-glucopyranosyloxy)methyl]-3-pyridinecarboxylic Acid (CAS 200111-50-8)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
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