(S)-1-((Benzyloxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid CAS 72180-27-9
| CAS No. | 72180-27-9 |
| Molecular Formula | C13H13F2NO4 |
| Molecular Weight | 285.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 285.24 g/mol gives (S)-1-((Benzyloxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(S)-1-((Benzyloxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid (CAS 72180-27-9), molecular formula C13H13F2NO4 and molecular weight 285.24 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H13F2NO4, (S)-1-((Benzyloxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 285.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (S)-1-((Benzyloxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13F2NO4 |
| Molecular Weight | 285.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- (R)-1-((Benzyloxy)carbonyl)-3,3-difluoropyrrolidine-2-carboxylic acid (CAS 1263177-90-7)
- 1-((Benzyloxy)carbonyl)-3,3-difluoropyrrolidine-2-carboxylic acid (CAS 1779438-13-9)
- (S)-1-((Benzyloxy)carbonyl)-3,3-difluoropyrrolidine-2-carboxylic acid (CAS 1932488-08-8)
- (R)-1-((Benzyloxy)carbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid (CAS 2136867-31-5)
- (1-(Benzyloxy)-2-oxopiperidin-3-yl)phosphonic acid (CAS 2004714-48-9)
- 2-((((Benzyloxy)carbonyl)amino)methyl)benzoic acid (CAS 120916-49-6)
- 2-{[3-(benzyloxy)phenyl]formamido}acetic acid (CAS 1211741-22-8)
- 4-(((Benzyloxy)carbonyl)amino)-2-methylbenzoic acid (CAS 1292567-05-5)
Recommended Standards
- 5-(4-Fluorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 675830-44-1)
- (E)-4-(2,4-Difluorobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 676529-99-0)
- 8-(4-Fluorophenyl)-2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine (CAS 611240-72-3)
- (3-Fluoro-4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)methanamine (CAS 472964-41-3)
- Methyl 4-{[6-oxo-3-phenyl-4-(piperidin-1-yl)-1,6-dihydropyridazin-1-yl]methyl}benzoate (CAS 861208-95-9)
- 3-Bromo-4-((4-chlorobenzyl)oxy)benzamide (CAS 1706457-41-1)
- 3-(2-Oxo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[cd]indol-1(2H)-yl)piperidine-2,6-dione (CAS 2767648-27-9)
- (3R,4S)-4-aminooxolan-3-ol (CAS 190792-70-2)
- 2,4-Dichloropteridine (CAS 98138-05-7)
- 3-Bromo-6-chloro-2-fluorobenzonitrile (CAS 943830-79-3)
- N1-cyclohexyl-N1-ethyl-N2-methylethane-1,2-diamine (CAS 933719-65-4)
- Leflunomide EP Impurity F (CAS 1403564-06-6)
- 2-Amino-4-(trifluoromethoxy)benzoic acid (CAS 1259323-62-0)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com