Salbutamol Glyoxal Impurity CAS 72189-44-7
| CAS No. | 72189-44-7 |
| Molecular Formula | C9H10O5 |
| Molecular Weight | 198.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Salbutamol Glyoxal Impurity (CAS 72189-44-7, C9H10O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Salbutamol Glyoxal Impurity is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10O5 |
| Molecular Weight | 198.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
Related Salbutamol Standards
- Salbutamol Glyoxal Impurity (CAS CATO-C4X-1176167)
- R-Salbutamol Glyoxal Impurity (CAS CATO-C4X-1176205)
- Salbutamol Impurity 38 (CAS CATO-C4X-117638)
- Salbutamol Impurity 107 (CAS 66654-06-6)
- Salbutamol Impurity 100 (CAS 16475-90-4)
- Salbutamol Impurity 177 (CAS CATO-C4X-1176177)
- Salbutamol EP Impurity H (CAS 132183-64-3)
- Salbutamol Impurity 194 (CAS CATO-C4X-1176194)
Recommended Standards
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- 3-(Hydroxymethyl)-2-methylbenzonitrile (CAS 1260024-34-7)
- (R)-1-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)pyrrolidin-3-amine (CAS 143112-51-0)
- (4-Heptylphenyl)(6-methylpyridin-3-yl)methanone (CAS 1187171-07-8)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
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