Amlodipine Besylate EP Impurity B CAS 721958-72-1
| CAS No. | 721958-72-1 |
| Molecular Formula | C29H32ClN3O7 |
| Molecular Weight | 570.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Amlodipine Besylate EP Impurity B (CAS 721958-72-1) is a certified pharmaceutical impurity reference standard with the molecular formula C29H32ClN3O7 and a molecular weight of 570.03 g/mol.
Based on its molecular formula C29H32ClN3O7, Amlodipine Besylate EP Impurity B contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 570.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H32ClN3O7 |
| Molecular Weight | 570.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amlodipine Standards
- Amlodipine Besilate EP Impurity B (CAS CATO-C4X-109562)
- Amlodipine N-Galactopyranoside (Mixture of Diastereomers) (CAS CATO-C4X-109511)
- Amlodipine Impurity 152 (CAS CATO-C4X-1095152)
- Amlodipine N-Glucose (CAS CATO-C4X-109546)
- Amlodipine Impurity 98 (CAS CATO-C4X-109598)
- Amlodipine Impurity 104 (CAS CATO-C4X-1095104)
- Amlodipine Impurity 106 (CAS CATO-C4X-1095106)
- Amlodipine Impurity 107 (CAS CATO-C4X-1095107)
Recommended Standards
- 5-(2,6-Dibromo-4-iodophenoxy)-2-phenyl-2H-indazole (CAS 918946-31-3)
- 2,4,6-Tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-1,3,5,2,4,6-trioxatriborinane (CAS 322471-05-6)
- 41836-28-6 Tris N,N-bis(trimethylsilyl)amide yttrium (III), min. 98% (99.9%-Y) (REO) (CAS 41836-28-6)
- 6-Chloro-N-(3-(trifluoromethyl)benzyl)-9-trityl-9H-purin-2-amine (CAS 1384265-26-2)
- Blonanserin Impurity 35 (CAS CATO-C4X-111035)
- Orforglipron Impurity 42 (CAS 2212021-92-4)
- Ceftriaxone Impurity 34 (CAS 1637561-91-1)
- 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine (CAS 1393545-06-6)
- 5-(fluoromethyl)pyrazine-2-carboxylic acid (CAS 1262803-66-6)
- 4-Ethyl-2-methoxypyridine (CAS 98593-17-0)
- Dolutegravir Impurity N13 (CAS 1246616-73-8)
- (1R)-2,2-difluorocyclopropan-1-amine hydrochloride (CAS 2089150-96-7)
- 3-Methyl-6-phenylimidazo[2,1-b]thiazole-2-carboxylic acid (CAS 446829-85-2)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com