Chlorpromazine Hydrochloride EP Impurity F CAS 72372-62-4
| CAS No. | 72372-62-4 |
| Molecular Formula | C17H19ClN2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Chlorpromazine Hydrochloride EP Impurity F (CAS 72372-62-4) is a certified pharmaceutical impurity reference standard with the molecular formula C17H19ClN2SHCl and a molecular weight of 355.32 g/mol.
Based on its molecular formula C17H19ClN2SHCl, Chlorpromazine Hydrochloride EP Impurity F contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 355.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H19ClN2S HCl |
| Molecular Weight | 355.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorpromazine Standards
- Chlorpromazine N-Oxide Sulfoxide (CAS 10404-90-7)
- Chlorpromazine EP Impurity D (CAS 1225-64-5)
- Chlorpromazine-D6 hydrochloride (CAS 1228182-46-4)
- Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6) (CAS 1276197-23-9)
- Chlorpromazine-13C,d3 Hydrochloride (CAS 1329612-87-4)
- Chlorpromazine Sulphoxide N-Oxide Maleate (CAS 150111-59-4)
- Chlorpromazine impurity 18 HCl (CAS 15502-93-9)
- Chlorpromazine Impurity 12 (CAS 1672-76-0)
Recommended Standards
- Valproate impurity 91 (CAS CATO-C4X-116691)
- Moxifloxacin Impurity 19 (CAS 2445515-66-0(Free Base))
- LysoPE impurity 7 (CAS 92605-66-8)
- 3-Aminoquinoline-4-thiol (CAS 109543-48-8)
- Canagliflozin Impurity 61 (CAS CATO-C4X-112361)
- BMS-470539 (CAS 457893-92-4)
- 4-((3-Bromopyridin-2-yl)amino)-1-methylpyrrolidin-2-one (CAS 1881672-18-9)
- 3-Amino-6-bromo-4-(2-chlorophenyl)-2(1H)-quinolinone-d5 (CAS 1794793-32-0)
- ((1S,3R,4R)-2-(2,2-Difluoroethyl)-2-azabicyclo[2.2.1]heptan-3-yl)methanol (CAS 2454490-62-9)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
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