(s)-5-(Fluoromethyl)pyrrolidin-2-one CAS 72479-03-9
| CAS No. | 72479-03-9 |
| Molecular Formula | C5H8FNO |
| Molecular Weight | 117.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (s)-5-(Fluoromethyl)pyrrolidin-2-one.
(s)-5-(Fluoromethyl)pyrrolidin-2-one (CAS 72479-03-9), molecular formula C5H8FNO and molecular weight 117.12 g/mol, is a CATO reference standard with documented purity and traceability.
(s)-5-(Fluoromethyl)pyrrolidin-2-one (C5H8FNO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H8FNO |
| Molecular Weight | 117.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related s Standards
- (R)-5-(Fluoromethyl)pyrrolidin-2-one (CAS 1412816-93-3)
- 3-(Fluoromethyl)piperidine (CAS 116574-73-3)
- 2-(Fluoromethyl)piperidine (CAS 1240528-86-2)
- (2R)-2-(Fluoromethyl)piperidine (CAS 1344580-68-2)
- 1-[2-(fluoromethyl)cyclobutyl]methanamine (CAS 1421606-00-9)
- (R)-3-(fluoromethyl)piperidine (CAS 1444103-49-4)
- (2S)-2-(Fluoromethyl)piperidine (CAS 886358-35-6)
- (S)-3-(fluoromethyl)piperidine (CAS 2306246-72-8)
Recommended Standards
- (3R)-3-fluoropiperidin-4-one (CAS 1638784-43-6)
- 1-(3-fluoroazetidin-3-yl)ethanone (CAS 2231674-01-2)
- (3S)-3-fluoropiperidin-4-one (CAS 1638784-41-4)
- 1-aminocyclobutane-1-carbonyl fluoride (CAS 2090728-55-3)
- 2-(5-(1,3-Dioxan-2-yl)thiophen-3-yl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 2096997-78-1)
- 4-(5-Bromo-1H-indol-3-yl)butan-2-one (CAS 552314-85-9)
- Dimethoxydi-p-tolylsilane (CAS 92779-72-1)
- Tert-butyl (S)-(1-aminopropan-2-yl)(methyl)carbamate (CAS 1268520-78-0)
- Butenafine Impurity 14 (CAS 124830-38-2)
- 1-(5-chloro-4-nitro-pyrazol-1-yl)-2-methyl-propan-2-ol (CAS 1415099-67-0)
- 2,5-Dichloro-N,N-diethylbenzenesulfonamide (CAS 4821-29-8)
- (S)-2,2-Dimethyl-1-(m-tolyl)propan-1-amine (CAS 100485-67-4)
- Carbonochloridic acid, 3-fluoro-4-methylphenyl ester (CAS 331746-01-1)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
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