2-Hydroxy-3-(trifluoromethyl)aniline CAS 72534-45-3
| CAS No. | 72534-45-3 |
| Molecular Formula | C7H6F3NO |
| Molecular Weight | 177.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Hydroxy-3-(trifluoromethyl)aniline.
2-Hydroxy-3-(trifluoromethyl)aniline (CAS 72534-45-3), molecular formula C7H6F3NO and molecular weight 177.12 g/mol, is a CATO reference standard with documented purity and traceability.
2-Hydroxy-3-(trifluoromethyl)aniline (C7H6F3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Hydroxy-3-(trifluoromethyl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NO |
| Molecular Weight | 177.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Amino-4-(trifluoromethyl)phenol (CAS 454-81-9)
- 2-Methoxy-4-(trifluoromethyl)pyridine (CAS 219715-34-1)
- 2,2-Difluoro-1-(5-fluoropyridin-2-yl)ethan-1-ol (CAS 2169580-50-9)
- 2-Methoxy-6-(trifluoromethyl)pyridine (CAS 34486-18-5)
- 2-Chloro-1-(3,5-difluorophenyl)ethan-1-one (CAS 920023-60-5)
- 8-Aminobicyclo[3.2.1]octane-3-carboxylic acid (CAS 1334149-38-0)
- Ethoxyacetic Acid (CAS 627-03-2)
- N-((2,5-Dioxopyrrolidin-1-yl)methyl)-N-methylbenzenesulfonamide (CAS 72802-68-7)
- Ethyl (E)-2-(2-(((((4-nitrobenzyl)oxy)amino)methylene)amino)thiazol-4-yl)benzoate (CAS 339010-25-2)
- tert-butyl 7-(chlorosulfonyl)-3,4-dihydro-2H-1,4-benzoxazine-4-carboxylate (CAS 1955540-74-5)
- (S)-2-mercaptobutanoic acid (CAS 1242881-37-3)
- 2,2,2-trifluoroethyl N-{4-[cyclohexyl(methyl)amino]-3-fluorophenyl}carbamate hydrochloride (CAS 1315366-48-3)
- 5-(3-Ethylbenzo[d]oxazol-2(3H)-ylidene)-3-phenyl-2-thioxothiazolidin-4-one (CAS 25962-16-7)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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