Adenosine Impurity 32 CAS 72560-66-8
| CAS No. | 72560-66-8 |
| Molecular Formula | C14H16N4O7 |
| Molecular Weight | 352.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Adenosine Impurity 32 (C14H16N4O7) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Adenosine Impurity 32 (CAS 72560-66-8, C14H16N4O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16N4O7 |
| Molecular Weight | 352.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 4 |
Related Adenosine Standards
- Adenosine Impurity 31 (CAS 4152-78-7)
- Adenosine Impurity 33 (CAS 62420-33-1)
- Adenosine 5’-Monophosphate-13C5 (CAS CATO-CCFD200542)
- Adenosine-2,3-O-phenylboronate (CAS 4710-68-3)
- Adenosine 2′-monophosphate (CAS 130-49-4)
- Adenosine Impurity 12 (CAS 25030-31-3)
- Adenosine Impurity 19 (CAS 166735-83-7)
- Adenosine Impurity 20 (CAS 77530-02-0)
Recommended Standards
- Mianserin impurity 32 (CAS CATO-C4X-136932)
- Benzyl 6-(ethylcarbamoyl)-4-(trifluoromethyl)pyridine-2-carboxylate (CAS 1209347-26-1)
- n-(Adamantan-1-yl)-2-chloro-n-[(4-chlorophenyl)methyl]acetamide (CAS 771500-68-6)
- N2-ethyl-N6-(pyridin-2-ylmethyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide (CAS 1211290-55-9)
- Gabapentin Impurity 8 HCl (CAS 1083246-63-2)
- Gefitinib impurity 66 (CAS CATO-C4X-111766)
- Regorafenib Impurity 71 (CAS CATO-C4X-104771)
- [4-(Pyridin-2-ylmethyl)oxan-4-yl]methanamine (CAS 1393427-44-5)
- 6-Butyl-7-hydroxy-3-(2-methylthiazol-4-yl)-4h-chromen-4-one (CAS 294853-21-7)
- (4-Bromo-3-(difluoromethyl)-5-fluoropyridin-2-yl)methanol (CAS 1805396-70-6)
- Homodihydrocapsaicin I (CAS 20279-06-5)
- 6-Methoxy-2-(4-methoxyphenyl)-1H-indole-3-carbaldehyde (CAS 158611-24-6)
- 2-(Difluoromethyl)-3-hydroxypyridine-4-carbonyl chloride (CAS 1805322-13-7)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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