Fluorescein Impurity 5 CAS 7262-41-1
| CAS No. | 7262-41-1 |
| Molecular Formula | C22H14O6 |
| Molecular Weight | 374.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluorescein Impurity 5.
CATO supplies Fluorescein Impurity 5 (CAS 7262-41-1), a pharmacopoeial impurity reference standard (molecular formula C22H14O6, MW 374.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H14O6, Fluorescein Impurity 5 contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 374.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fluorescein Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H14O6 |
| Molecular Weight | 374.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Fluorescein Standards
- Fluorescein-6-isothiocyanate (CAS 18861-78-4)
- 6-Fluorescein Isothiocyanate (CAS 3326-31-6)
- Fluorescein-O'-acetic Acid (CAS 233759-98-3)
- Fluorescein Impurity 12 (CAS CATO-C4X-290012)
- Fluorescein Impurity 3 (CAS 1428447-91-9)
- Fluorescein Methyl ester (CAS 70672-06-9)
- Fluorescein Impurity 7 (CAS CATO-C4X-29007)
- Fluorescein<I>o</I>-acrylate (CAS 193419-86-2)
Recommended Standards
- 5,2'-dihydroxy-6,7,8,6'-tetramethoxyflavone 5-hydroxy-2-(2-hydroxy-6-methoxy-phenyl)-6,7,8-trimethoxy-chromen-4-one 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one 55084-08-7 CHEBI:9061 neobaicalein scullcapflavone II skullcapflavone II (CAS 55084-08-7)
- Vitexicarpin (CAS 479-91-4)
- Thalidomide-5'-O-C4-acid (CAS 2226301-24-0)
- Geniposidic Acid (CAS 27741-01-1)
- Ceritinib Impurity 19 (CAS 771555-72-7)
- Ornidazole impurity 50 (CAS CATO-C4X-133150)
- Acetylcysteine impurity 65 (CAS 282727-77-9（free base）)
- (3-Chloro-4-iodophenyl)methanamine (CAS 687623-52-5)
- 3-((2,5-Dimethoxyphenyl)sulfonyl)-2H-chromen-2-one (CAS 866346-80-7)
- Fesoterodine Impurity O (CAS 250214-69-8)
- 1-Fluoro-2-methoxy-3-vinylbenzene (CAS 499235-07-3)
- (3-Methyl-1H-indazol-7-yl)methanamine (CAS 1552214-93-3)
- 1-(2-chloro-4-pyrimidinyl)-4-piperidinecarboxylic acid methyl ester 889126-33-4 A842999 methyl 1-(2-chloranylpyrimidin-4-yl)piperidine-4-carboxylate (CAS 889126-33-4)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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