N-(4-Fluorophenyl)-4-methylbenzenesulfonamide CAS 727-31-1

Purity 97%+In StockPharmaceutical Standards
CAS No.727-31-1
Molecular FormulaC13H12FNO2S
Molecular Weight265.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Fluorophenyl)-4-methylbenzenesulfonamide CAS 727-31-1 chemical structure

Description

The occurrence of N-(4-Fluorophenyl)-4-methylbenzenesulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(4-Fluorophenyl)-4-methylbenzenesulfonamide (CAS 727-31-1) is a high-purity analytical reference standard with the molecular formula C13H12FNO2S and a molecular weight of 265.30 g/mol.

Based on its molecular formula C13H12FNO2S, N-(4-Fluorophenyl)-4-methylbenzenesulfonamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Fluorophenyl)-4-methylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H12FNO2S
Molecular Weight265.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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