2-Bromo-1,6-naphthyridine CAS 72754-06-4

Purity 97%+In StockPharmaceutical Standards
CAS No.72754-06-4
Molecular FormulaC8H5BrN2
Molecular Weight209.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-1,6-naphthyridine CAS 72754-06-4 chemical structure

Description

The occurrence of 2-Bromo-1,6-naphthyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Bromo-1,6-naphthyridine (CAS 72754-06-4) is a high-purity analytical reference standard with the molecular formula C8H5BrN2 and a molecular weight of 209.04 g/mol.

The molecular framework of 2-Bromo-1,6-naphthyridine (C8H5BrN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Bromo-1,6-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H5BrN2
Molecular Weight209.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1977
Halogen ContentBr-containing
Nitrogen Atoms2

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