Pantoprazole Chloromethyl Impurity CAS 72830-09-2
| CAS No. | 72830-09-2 |
| Molecular Formula | C8H10ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pantoprazole Chloromethyl Impurity is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Pantoprazole Chloromethyl Impurity (CAS 72830-09-2, C8H10ClNO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H10ClNO2HCl, Pantoprazole Chloromethyl Impurity contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 224.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO2 HCl |
| Molecular Weight | 224.08 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pantoprazole Standards
- Pantoprazole Magnesium Salt (CAS 1022083-88-0)
- Pantoprazole EP Impurity B (CAS 102625-64-9)
- Pantoprazole (CAS 102625-70-7)
- Pantoprazole Impurity 33 (CAS 102625-99-0)
- Pantoprazole Impurity 42 (CAS 107512-34-5)
- Pantoprazole Impurity 34 (CAS 107512-35-6)
- Pantoprazole Impurity 45 (CAS 1166386-02-2)
- Pantoprazole Sulfide-D7 (Major) (CAS 1189977-42-1)
Recommended Standards
- Paliperidone Impurity 80 (CAS 130049-87-5)
- Olaparib Impurity 137 (CAS CATO-C4X-1135137)
- Lifitegrast Impurity 116 (CAS CATO-C4X-2409116)
- 2-Hydroxy-N-(thiazol-2-yl)benzamide (CAS 130234-70-7)
- {7-methylimidazo[1,2-a]pyridin-2-yl}methanamine (CAS 880361-79-5)
- N-methyl-2-(thiophen-2-yl)ethan-1-amine hydrochloride (CAS 7404-71-9)
- 4-[(2-Furylmethyl)amino]-3-nitrobenzoic acid (CAS 284672-98-6)
- 4-(Aminomethyl)-2-ethoxyphenol hydrochloride (CAS 105026-85-5)
- 2-Amino-3-(7-methoxy-1H-indol-3-yl)propanoic acid (CAS 16979-62-7)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com