Olaparib Impurity 137 CAS CATO-C4X-1135137
| CAS No. | CATO-C4X-1135137 |
| Molecular Formula | C11H13O5P |
| Molecular Weight | 256.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 256.19 g/mol gives Olaparib Impurity 137 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Olaparib Impurity 137 (CAS CATO-C4X-1135137, C11H13O5P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Olaparib Impurity 137 (C11H13O5P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13O5P |
| Molecular Weight | 256.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Olaparib Standards
- Olaparib Impurity 36 (CAS CATO-C4X-113536)
- Olaparib Impurity 26 (CAS 414910-15-9)
- Olaparib Impurity 115 (CAS CATO-C4X-1135115)
- Olaparib Impurity 19 (CAS CATO-C4X-113519)
- Olaparib Impurity 153 (CAS CATO-C4X-1135153)
- Olaparib impurity 139 (CAS 42086-73-7)
- Olaparib Impurity 20 (CAS CATO-C4X-113520)
- Olaparib Impurity 131 (CAS CATO-C4X-1135131)
Recommended Standards
- Norbaeocystin (CAS 21420-59-7)
- Ethyl 2-((4-fluoro-3-nitrophenyl)amino)-2-oxoacetate (CAS 69066-09-7)
- Fulvestrant Impurity 8 (CAS 252947-01-6)
- 4-((2-Fluoro-5-nitrophenyl)amino)-4-oxobutanoic acid (CAS 314281-85-1)
- Norepinephrine Impurity 111 (CAS 2947-04-8)
- Cetylpyridinium Chloride Impurity 1 (CAS CATO-C4X-27871)
- Norepinephrine Impurity 48 (CAS CATO-C4X-151468)
- Pyridine-2,3-dicarbaldehyde (CAS 4663-93-8)
- (1-Methyl-5-phenyl-1H-pyrazol-4-yl)boronic acid (CAS 1858252-28-4)
- Abemaciclib Impurity 40 (CAS CATO-C4X-293740)
- Propyl[(2,3,4-trimethoxyphenyl)methyl]amine (CAS 893574-38-4)
- 3,4-Dimethyl-5-oxo-2,5-dihydro-1H-pyrazole-1-carboxamide (CAS 857220-41-8)
- Venetoclax Impurity 108 (CAS CATO-C4X-2495108)
- Gastrin Tetrapeptide (CAS 1947-37-1)
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