Ethyl 2-(2-chloropropanamido)-4-phenylthiophene-3-carboxylate CAS 728898-92-8
| CAS No. | 728898-92-8 |
| Molecular Formula | C16H16ClNO3S |
| Molecular Weight | 337.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 2-(2-chloropropanamido)-4-phenylthiophene-3-carboxylate (C16H16ClNO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ethyl 2-(2-chloropropanamido)-4-phenylthiophene-3-carboxylate (CAS 728898-92-8), a certified reference material (molecular formula C16H16ClNO3S, MW 337.82 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO3S |
| Molecular Weight | 337.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-(2-chloropropanamido)-5-phenylthiophene-3-carboxylate (CAS 565165-67-5)
- Ethyl 2-(3-chloropropanamido)-4-phenylthiophene-3-carboxylate (CAS 355003-70-2)
- Methyl 2-(4-(3-chloropropanamido)phenoxy)benzoate (CAS 866020-20-4)
- 3-(3-Chloropropanamido)-N-phenylbenzofuran-2-carboxamide (CAS 887884-78-8)
- Ethyl 2-(2-chloropropanamido)-4-methyl-5-(methylcarbamoyl)thiophene-3-carboxylate (CAS 1311316-22-9)
- 4-(2-Chloropropanamido)-n-(2-methoxyphenyl)benzamide (CAS 790270-96-1)
- ethyl 2-(3-chloropropanamido)-4-(thiophen-2-yl)thiophene-3-carboxylate (CAS 929971-63-1)
- Ethyl 2-(2-chloropropanamido)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 568544-05-8)
Recommended Standards
- Ethyl 2-(2-chloroacetamido)-5-methyl-4-phenylthiophene-3-carboxylate (CAS 565179-42-2)
- Ethyl 2-(2-chloroacetamido)-4-methyl-5-phenylthiophene-3-carboxylate (CAS 731820-85-2)
- 4-Chloro-N-(3-ethoxypropyl)-2,5-dimethoxybenzenesulfonamide (CAS 898645-83-5)
- Methyl 2-(2-chloroacetamido)-4-(2,5-dimethylphenyl)thiophene-3-carboxylate (CAS 667407-71-8)
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