Ethyl 2-(2-chloroacetamido)-4-methyl-5-phenylthiophene-3-carboxylate CAS 731820-85-2

Purity 97%+In StockPharmaceutical Standards
CAS No.731820-85-2
Molecular FormulaC16H16ClNO3S
Molecular Weight337.82 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 2-(2-chloroacetamido)-4-methyl-5-phenylthiophene-3-carboxylate CAS 731820-85-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Ethyl 2-(2-chloroacetamido)-4-methyl-5-phenylthiophene-3-carboxylate (CAS 731820-85-2), molecular formula C16H16ClNO3S and molecular weight 337.82 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, Ethyl 2-(2-chloroacetamido)-4-methyl-5-phenylthiophene-3-carboxylate (C16H16ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 337.82 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), Ethyl 2-(2-chloroacetamido)-4-methyl-5-phenylthiophene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H16ClNO3S
Molecular Weight337.82 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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