1-((6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid CAS 728916-77-6
| CAS No. | 728916-77-6 |
| Molecular Formula | C20H19BrFN3O2 |
| Molecular Weight | 432.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-((6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-((6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid (CAS 728916-77-6), molecular formula C20H19BrFN3O2 and molecular weight 432.29 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 1-((6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19BrFN3O2 |
| Molecular Weight | 432.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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Recommended Standards
- Crisaborole Impurity 146 (CAS CATO-C4X-2021146)
- 1-(4-Bromophenyl)-3-[4-(4-fluorophenyl)piperazin-1-yl]pyrrolidine-2,5-dione (CAS 299408-57-4)
- 2,2'-Dibromo-1,1'-binaphthalene 2-bromo-1-(2-bromonaphthalen-1-yl)naphthalene 74866-28-7 A9570 (CAS 74866-28-7)
- N'-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-4-fluoro-N'-methylbenzohydrazide (CAS 320417-56-9)
- tert-Butyl 1-(hydroxymethyl)-2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate (CAS 1357351-86-0)
- 3-Bromo-4-pyrrolidinobenzoic Acid (CAS 1131615-12-7)
- 3,4-Dihydrodibenzo[a,j]acridine (CAS 106589-49-5)
- 2-(Benzo[d]thiazol-2-yl)-5-bromophenol (CAS 90481-37-1)
- N-(4-isopropoxyphenyl)acetamide (CAS 7146-61-4)
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- 1-Methyl-N-(2-methylcyclopentyl)-1h-pyrazol-3-amine (CAS 1490858-65-5)
- Ethyl 4-[(4-chlorophenyl)sulfinyl]-3-oxobutanoate (CAS 337923-05-4)
- Neuropeptide Y, human (CAS 98264-90-5)
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