Chloro(methyl)(2-methyl-2-propanyl)(pentafluorophenyl)silane CAS 73000-03-0
| CAS No. | 73000-03-0 |
| Molecular Formula | C11H12ClF5Si |
| Molecular Weight | 302.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Chloro(methyl)(2-methyl-2-propanyl)(pentafluorophenyl)silane (C11H12ClF5Si) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Chloro(methyl)(2-methyl-2-propanyl)(pentafluorophenyl)silane (CAS 73000-03-0), molecular formula C11H12ClF5Si and molecular weight 302.74 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClF5Si |
| Molecular Weight | 302.74 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F/Cl-containing |
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- (E)-3-(3-chloro-4-methoxyphenyl)-1-(3-methoxyphenyl)prop-2-en-1-one (CAS 861207-60-5)
- 2-Chloro-N-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]propanamide (CAS 565165-72-2)
- 3-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1H-pyrazole (CAS 451485-60-2)
- 3-(3-Chloro-2-Methylphenyl)-2-(Fluoromethyl)Quinazolin-4(3H)-One (CAS 49700-31-4)
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Recommended Standards
- 3-(4-Chlorophenyl)-4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile (CAS 844499-52-1)
- Cyclophosphamide impurity 41 (CAS CATO-C4X-230641)
- Chlorodimethyl[3-(2,3,4,5,6-pentafluorophenyl)propyl]silane (CAS 157499-19-9)
- Methyl 2-(1-(2-chloroacetyl)-3-oxodecahydroquinoxalin-2-yl)acetate (CAS 1008857-93-9)
- 2-Amino-3-methylquinoline-6-carboxylic acid (CAS 2691878-18-7)
- 5-AMINO-2,4-DIMETHYLBENZONITRILE (CAS 856789-54-3)
- Sildenafil Drugs Mix 11 (CAS CATO-MCAD302083-ME)
- 6-Bromo-7-chloro-8-methyl-4-oxo-1H-quinoline-2-carboxylic acid (CAS 1820674-78-9)
- 1-Methoxy-8,9-dihydro-5H-benzo[7]annulen-7(6H)-one (CAS 1022957-91-0)
- Benzo[k]fluoranthene- (CAS 1397194-60-3)
- Tolvaptan Impurity 17 (CAS 1975-51-5)
- (5-((4-Bromophenyl)sulfonyl)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-cyanobenzoate (CAS 955976-45-1)
- 2-(2-Methoxyphenyl)piperidine-1-carbaldehyde (CAS 1355225-64-7)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
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