Ticlopidine EP Impurity E Bromide CAS 73099-88-4
| CAS No. | 73099-88-4 |
| Molecular Formula | C14H11ClNS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ticlopidine EP Impurity E Bromide (C14H11ClNSBr) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Ticlopidine EP Impurity E Bromide (CAS 73099-88-4, C14H11ClNSBr) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11ClNS Br |
| Molecular Weight | 340.66 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ticlopidine Standards
- Ticlopidine Impurity J (CAS 108896-78-2)
- Ticlopidine-d4 (CAS 1246817-49-1)
- ticlopidine Impurity 4 (CAS 138956-81-7)
- Ticlopidine EP Impurity J DiHCl (CAS 2056-18-0)
- Ticlopidine Hydrochloride - Impurity C (Hydrochloride Salt) (CAS 22680-44-0)
- Ticlopidine EP Impurity A (CAS 272-14-0)
- Ticlopidine Hydrochloride (CAS 53885-35-1)
- Ticlopidine - Impurity H (CAS 53885-39-5)
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