Roflumilast Impurity 7 CAS 1391053-75-0

Description

Compared with other compounds in its class, the molecular weight of 368.76 g/mol gives Roflumilast Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Roflumilast Impurity 7 (CAS 1391053-75-0) is a certified pharmaceutical impurity reference standard with the molecular formula C17H15ClF2N2O3 and a molecular weight of 368.76 g/mol.

The molecular framework of Roflumilast Impurity 7 (C17H15ClF2N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Roflumilast Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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