Tapentadol EP Impurity C CAS 731764-76-4
| CAS No. | 731764-76-4 |
| Molecular Formula | C14H21NO |
| Molecular Weight | 219.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Tapentadol EP Impurity C (CAS 731764-76-4, C14H21NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Tapentadol EP Impurity C is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 219.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Tapentadol EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H21NO |
| Molecular Weight | 219.32 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Tapentadol Standards
- Tapentadol EP Impurity D (CAS CATO-C4X-209920)
- Tapentadol EP Impurity A (CAS 454221-04-6)
- Tapentadol impurity 7 (CAS 387356-03-8)
- Tapentadol Impurity 14 (CAS CATO-C4X-209914)
- Tapentadol Impurity 16 (CAS CATO-C4X-209916)
- Tapentadol Impurity 10 (CAS 809282-30-2)
- Tapentadol EP Impurity E (CAS 175591-22-7)
- Tapentadol Impurity 18 (CAS CATO-C4X-209918)
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Why CATO?
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