2-Chloro-N-(2-((4-fluorophenyl)amino)-5-nitrophenyl)acetamide CAS 731802-59-8
| CAS No. | 731802-59-8 |
| Molecular Formula | C14H11ClFN3O3 |
| Molecular Weight | 323.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-N-(2-((4-fluorophenyl)amino)-5-nitrophenyl)acetamide.
2-Chloro-N-(2-((4-fluorophenyl)amino)-5-nitrophenyl)acetamide (CAS 731802-59-8) is a high-purity analytical reference standard with the molecular formula C14H11ClFN3O3 and a molecular weight of 323.71 g/mol.
Based on its molecular formula C14H11ClFN3O3, 2-Chloro-N-(2-((4-fluorophenyl)amino)-5-nitrophenyl)acetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 323.71 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11ClFN3O3 |
| Molecular Weight | 323.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
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- Methyl 4-(4-formyl-3,5-dimethoxyphenoxy)butanoate (CAS 250283-90-0)
- 5-Bromo-6-methylpyridine-2-carboxylic acid isopropyl ester (CAS 1122092-09-4)
- N,N'-Bis(4-formylphenyl)-N,N'-diphenylbenzidine (CAS 137911-28-5)
- 5-Iodo-2-methylpyridin-3-ol (CAS 1806474-86-1)
- 1-(1-(2-(3,5-Dimethylphenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol (CAS 887348-47-2)
- 2-Chloro-N,N-diisopropylbenzamide (CAS 70657-63-5)
- N-Ethyl-N-(imidazo[1,2-a]pyridin-3-ylmethyl)-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide (CAS 1448038-10-5)
- Alanyl Glutamine Impurity 23 (CAS CATO-C4X-197423)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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