Benzylpenicillin EP Impurity F (2R,4S-Isomer) CAS 73184-06-2
| CAS No. | 73184-06-2 |
| Molecular Formula | C15H20N2O3S |
| Molecular Weight | 308.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Benzylpenicillin EP Impurity F (2R,4S-Isomer) (C15H20N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Benzylpenicillin EP Impurity F (2R,4S-Isomer) (CAS 73184-06-2, C15H20N2O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O3S |
| Molecular Weight | 308.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Benzylpenicillin Standards
- Benzylpenicillin Impurity 48 (CAS CATO-C4X-189948)
- Benzylpenicillin EP Impurity F (CAS CATO-C4X-18996)
- Benzylpenicillin Impurity 11 (CAS 118-53-6)
- Benzylpenicillin EP Impurity G (CAS CATO-C4X-189935)
- Benzylpenicillin Potassium EP Impurity H (CAS 4493-18-9)
- Benzylpenicillin (Benzathine) tetrahydrate Impurity 24 (CAS 69239-61-8)
- Benzylpenicillin EP Impurity D (CAS 13093-87-3)
- Benzylpenicillin Impurity 54 (CAS 90962-63-3)
Recommended Standards
- Ertapenem Impurity 61 (CAS CATO-C4X-163361)
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- Gliclazide EP Impurity D (CAS 1136426-19-1)
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- N-Boc-N-n-propylethylenediamine, 97% (CAS 105628-64-6)
- tert-Butyl 3-fluoro-4-methylbenzoate (CAS 866625-11-8)
- Cis-2-tert-Butoxycarbonylamino-1-methyl-cyclopentanecarboxylic acid (CAS 1965310-30-8)
- 6-(sec-Butoxy)-2-((3-methoxyphenyl)thio)pyrimidin-4-amine (CAS 284681-52-3)
- 7-bromo-2,6-dichloro-5,8-difluoro-1H-quinazolin-4-one (CAS 2820536-73-8)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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