2-3-5-Tri-O-acetyl-N2-dimethylguanosine CAS 73196-87-9
| CAS No. | 73196-87-9 |
| Molecular Formula | C18H23N5O8 |
| Molecular Weight | 437.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-3-5-Tri-O-acetyl-N2-dimethylguanosine (CAS 73196-87-9), molecular formula C18H23N5O8 and molecular weight 437.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-3-5-Tri-O-acetyl-N2-dimethylguanosine (C18H23N5O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-3-5-Tri-O-acetyl-N2-dimethylguanosine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H23N5O8 |
| Molecular Weight | 437.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 5 |
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