Ampicillin EP Impurity H CAS 73200-73-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.73200-73-4
Molecular FormulaC10H8N2O
Molecular Weight172.18 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ampicillin EP Impurity H CAS 73200-73-4 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies Ampicillin EP Impurity H (CAS 73200-73-4), a pharmacopoeial impurity reference standard (molecular formula C10H8N2O, MW 172.18 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ampicillin EP Impurity H (C10H8N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC10H8N2O
Molecular Weight172.18 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1977
Nitrogen Atoms2

Related Ampicillin Standards

Recommended Standards

Why CATO?