Triclabendazole EP Impurity A CAS 100648-13-3
| CAS No. | 100648-13-3 |
| Molecular Formula | C14H9Cl3N2O2S |
| Molecular Weight | 375.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Triclabendazole EP Impurity A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 375.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Triclabendazole EP Impurity A (CAS 100648-13-3) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9Cl3N2O2S and a molecular weight of 375.66 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Triclabendazole EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl3N2O2S |
| Molecular Weight | 375.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Triclabendazole Standards
- Triclabendazole Impurity 3 (CAS 145770-88-3)
- Triclabendazole Impurity 4 (CAS 145770-89-4)
- Triclabendazole (CAS 68786-66-3)
- Triclabendazole Impurity 5 (CAS 106791-37-1)
- Triclabendazole EP Impurity B (CAS 68828-69-3)
- Triclabendazole EP Impurity D (CAS 118353-04-1)
- Triclabendazole sulfoxide(Sodium) (CAS 2077198-33-3)
- Triclabendazole Impurity N1 (CAS CATO-CP116696)
Recommended Standards
- (R)-1-(4-(((tert-butyldimethylsilyl)oxy)methyl)cyclohexyl)-N-((R)-1-phenylethyl)ethanamine (CAS 672314-45-3)
- Silver molybdate (CAS 13765-74-7)
- 3-Methyl-N-(2,2,2-trichloro-1-((2-fluorophenyl)amino)ethyl)benzamide (CAS 5364-22-7)
- 5-Amino-n-(2-bromo-5-methylphenyl)-2-chlorobenzene-1-sulfonamide (CAS 522606-36-6)
- Xanomeline Impurity 18 Fumarate (CAS CATO-C4X-330134)
- Aspirin Impurity 17 (CAS 77527-00-5)
- Saxagliptin Impurity 8 (CAS 1445592-86-8)
- 2-(4-Chloro-3-(difluoromethyl)-5-hydroxypyridin-2-yl)acetic acid (CAS 1806938-98-6)
- Methyl 5-bromo-3-methoxybenzofuran-2-carboxylate (CAS 1779122-12-1)
- 8-Chloro-2-(4-hydroxyphenyl)quinoline-4-carboxylic acid (CAS 861236-55-7)
- 7-Hydroxy-2-isopropyl-3-phenylquinazolin-4(3H)-one (CAS 1272758-34-5)
- N-Benzyl-2-fluoro-5-hydroxybenzamide (CAS 1881322-17-3)
- 2-(3-Chloro-4-methoxyphenyl)-2-hydroxyacetic acid (CAS 23982-26-5)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
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