2-[2-chloro-5-(trifluoromethyl)benzenesulfonamido]acetic acid CAS 732291-51-9
| CAS No. | 732291-51-9 |
| Molecular Formula | C9H7ClF3NO4S |
| Molecular Weight | 317.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[2-chloro-5-(trifluoromethyl)benzenesulfonamido]acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-[2-chloro-5-(trifluoromethyl)benzenesulfonamido]acetic acid (CAS 732291-51-9), molecular formula C9H7ClF3NO4S and molecular weight 317.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-[2-chloro-5-(trifluoromethyl)benzenesulfonamido]acetic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 317.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[2-chloro-5-(trifluoromethyl)benzenesulfonamido]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF3NO4S |
| Molecular Weight | 317.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- ethyl 5-(chlorosulfonyl)-2-(trifluoromethyl)pyridine-3-carboxylate (CAS 1803595-99-4)
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- rel-(3R,4R)-3-Aminotetrahydro-2H-pyran-4-carboxylic acid (CAS 1233010-36-0)
- 8-Chloro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 1269530-65-5)
- (2R,3S)-2,3-diphenylsuccinic acid (CAS 1225-13-4)
- 3,5-Bis(pyridin-4-ylethynyl)benzoic acid (CAS 2243148-99-2)
- 7-Methoxy-5-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine (CAS 1520510-34-2)
- 2-(Trifluoromethyl)-3H-imidazo[4,5-c]pyridine (CAS 19918-36-6)
- 2-(Tert-butyl) 9-methyl 2-azaspiro[5.5]Undecane-2,9-dicarboxylate (CAS 1624799-96-7)
- (1H-benzo[d]imidazol-2-yl)(4-((3-chloropyrazin-2-yl)oxy)phenyl)methanone (CAS 1227065-24-8)
- 3-Chloro-4-[(3-fluorobenzyl)oxy]benzaldehyde (CAS 433244-56-5)
- Peptide Impurity 82 (CAS 10491-78-8)
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