Rupatadine Impurity 44 CAS 732962-71-9
| CAS No. | 732962-71-9 |
| Molecular Formula | C27H26ClN3O2 |
| Molecular Weight | 459.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Rupatadine Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Rupatadine Impurity 44 (CAS 732962-71-9) is a certified pharmaceutical impurity reference standard with the molecular formula C27H26ClN3O2 and a molecular weight of 459.97 g/mol.
The molecular framework of Rupatadine Impurity 44 (C27H26ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C27H26ClN3O2 |
| Molecular Weight | 459.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rupatadine Standards
- Rupatadine Impurity 45 (CAS CATO-C4X-102745)
- Rupatadine Impurity 46 (CAS CATO-C4X-102746)
- Rupatadine impurity 32 (CAS CATO-C4X-102732)
- Rupatadine Impurity 43 (CAS CATO-C4X-102743)
- Rupatadine Impurity 16 (CAS CATO-C4X-102716)
- Rupatadine impurity 17 (CAS CATO-C4X-102717)
- Rupatadine impurity 7 (CAS 1704730-21-1)
- Rupatadine impurity 8 (CAS CATO-C4X-10278)
Recommended Standards
- 2-(5-(5-Chloro-1,3-dimethyl-1H-benzo[d]imidazol-2(3H)-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-phenylpropanoic acid (CAS 84712-65-2)
- 1H,1H-Tridecafluoroheptyl Iodide (CAS 212563-43-4)
- (S)-tert-Butyl 1-(chloromethyl)-5-((4-methylpiperazine-1-carbonyl)oxy)-1H-benzo[e]indole-3(2H)-carboxylate (CAS 244154-66-3)
- 4-(Difluoromethyl)-2,5-diiodopyridine-3-sulfonamide (CAS 1804694-43-6)
- Sugammadex sodium Impurity Org198958-2 (CAS 2412953-13-8)
- Acetazolamide EP Impurity E (CAS 827026-60-8)
- Indometacin Impurity 64 (CAS CATO-C4X-147064)
- Isopropyl 2-((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)acetate (CAS 445384-85-0)
- 4-Bromo-7-methylisobenzofuran-1(3H)-one (CAS 1179362-74-3)
- Methyl 5-(hydroxymethyl)thiazole-2-carboxylate (CAS 2090916-35-9)
- 1-(p-Tolyl)-1H-pyrazol-4-amine (CAS 90839-86-4)
- Methyl 4-methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate (CAS 343864-83-5)
- 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarbonyl chloride (CAS 1004294-65-8)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com