Lysine Impurity 44 CAS 73343-51-8
| CAS No. | 73343-51-8 |
| Molecular Formula | C12H26N4O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lysine Impurity 44 (CAS 73343-51-8, C12H26N4O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H26N4O3HCl, Lysine Impurity 44 contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 310.82 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lysine Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H26N4O3 3*HCl |
| Molecular Weight | 310.82 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lysine Standards
- L-Lysine Hydrochloride (CAS 10098-89-2)
- D-Lysine dihydrochloride (CAS 10303-72-7)
- Lysine Impurity 10 HCl (CAS 104584-11-4)
- L-Lysine-13C6,15N2 Hydrochloride (CAS 1200447-00-2)
- L-lysine-6-<SUP>13</SUP>C dihydrochloride (CAS 1217466-44-8)
- Lysine Impurity 25 (CAS 121893-23-0)
- Lysine Impurity 16 TFA Salt (CAS 13184-13-9(free base))
- L-Lysine-d4 Methyl Ester Dihydrochloride (CAS 1331896-92-4)
Recommended Standards
- Amiodarone Impurity HCl (CAS CATO-C4X-142546)
- Nintedanib Impurity 18 (CAS CATO-C4X-181418)
- Doxorubicin Impurity 8 (CAS 20982-41-6)
- Methyl 4-fluoro-3-(prop-2-yn-1-yloxy)benzoate (CAS 214822-98-7)
- 3-Oxo-4-(4-trifluoromethylphenyl)butanoyl chloride (CAS 1987320-88-6)
- 1-(2-Fluorophenyl)cyclobutane-1-carbonyl chloride (CAS 151157-31-2)
- 4-bromo-3-fluoro-2-iodobenzoic acid (CAS 1823316-00-2)
- (4R,4'R)-2,2'-Cyclohexylidenebis[4-tert-butyl-4,5-dihydrooxazole] (CAS 2757082-26-9)
- 3-Oxo-2-propyl-2,3,5,6,7,8-hexahydrocinnoline-6-carboxylic acid (CAS 1713714-14-7)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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