6-(4-Methoxyphenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine CAS 73474-78-9
| CAS No. | 73474-78-9 |
| Molecular Formula | C13H9F3N4O2 |
| Molecular Weight | 310.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(4-Methoxyphenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine.
6-(4-Methoxyphenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 73474-78-9), molecular formula C13H9F3N4O2 and molecular weight 310.23 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H9F3N4O2, 6-(4-Methoxyphenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 310.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9F3N4O2 |
| Molecular Weight | 310.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methoxyphenoxy Standards
- 6-(3-Methoxyphenoxy)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 73474-77-8)
- 2-(2-Methoxyphenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 893696-91-8)
- 5-((3-Methoxyphenoxy)methyl)-4-(3-methoxypropyl)-4H-1,2,4-triazole-3-thiol (CAS 917746-61-3)
- N-(4-(2-Methoxyphenoxy)but-2-yn-1-yl)-2-methylbenzamide (CAS 1421481-37-9)
- Ethyl 2-(2-((2-methoxyphenoxy)methyl)morpholino)acetate (CAS 1706449-65-1)
- Ethyl 2-(2-((4-methoxyphenoxy)methyl)morpholino)acetate (CAS 1706454-53-6)
- 5-(o-Methoxyphenoxy)-4,6-dihydroxy-2-(4-pyridyl)pyrimidine (CAS 150728-08-8)
- 1-(2-(2-Methoxyphenoxy)ethyl)-5-methylindoline-2,3-dione (CAS 620931-53-5)
Recommended Standards
- 2,3,5,6-Tetrafluoro-4-((6-hydroxyhexyl)oxy)benzoicacid (CAS 1017789-70-6)
- 4-Nitro-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 3319-17-3)
- 3,5-dimethyl-1-(oxan-2-yl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1126779-11-0)
- 3-Bromo-N-cyclooctylbenzamide (CAS 549478-23-1)
- O-Cyclopentylhydroxylamine (CAS 76029-50-0)
- 6-(3-Methylpyridin-2-yl)pyridine-3-carboxylic acid (CAS 2091327-64-7)
- N-(Furan-2-ylmethyl)-5-methyl-N-(thiophen-3-ylmethyl)isoxazole-4-carboxamide (CAS 1448052-40-1)
- 2-(3-Bromophenyl)-2-methylpropanenitrile (CAS 90433-20-8)
- N-(2-aminoethyl)-5-bromopyridine-2-carboxamide hydrochloride (CAS 103878-71-3)
- 4-[[[4-[(4-bromo-2-fluorophenyl)amino]-6-methoxy-7-quinazolinyl]oxy]methyl]-1-Piperidinecarboxylic acid 1,1-dimethylethyl ester (CAS 338992-20-4)
- 7-Bromo-4-methylchroman-4-ol (CAS 2643353-57-3)
- 5,6-Dimethylpyrazine-2,3-diamine (CAS 53114-83-3)
- Afoxolaner impurity 11 (CAS CATO-C4X-31381)
- 149471-11-4 Neuropeptide DF2 L-Phenylalaninamide, L-alpha-aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl- Asp-arg-asn-phe-leu-arg-phe-NH2 Aspartyl-arginyl-asparaginyl-phenylalanyl-leucyl-arginyl-phenylalaninamide L-alpha-Aspartyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide DF(2) Neuropeptide Drnflrfamide (CAS 149471-11-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com