Nifuroxazide EP Impurity D CAS 736-53-8
| CAS No. | 736-53-8 |
| Molecular Formula | C10H6N4O6 |
| Molecular Weight | 278.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nifuroxazide EP Impurity D (CAS 736-53-8) is a certified pharmaceutical impurity reference standard with the molecular formula C10H6N4O6 and a molecular weight of 278.18 g/mol.
Structurally, Nifuroxazide EP Impurity D (C10H6N4O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 278.18 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nifuroxazide EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6N4O6 |
| Molecular Weight | 278.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
Related Nifuroxazide Standards
Recommended Standards
- 9-(2,3-Dichloropropyl)-9H-carbazole (CAS 300816-36-8)
- 4,5-Dimethoxy-2-(2,2,2-trifluoroacetyl)benzoic acid (CAS 2654746-66-2)
- tert-butyl (3R)-3-(bromomethyl)piperidine-1-carboxylate (CAS 1002359-91-2)
- 3-[[2-Nitro-4-(trifluoromethyl)phenyl]amino]propanoic Acid (CAS 37040-43-0)
- Delamanid Impurity N1 (CAS 287952-66-3)
- Posaconazole Impurity 167 (CAS CATO-C4X-1208167)
- Apalutamide Impurity 9 (CAS 2894796-78-0)
- 5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (CAS 7135-02-6)
- 1076198-61-2 6-(Benzyloxy)-2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfanyl)-1H-benzimidazole DTXSID90652658 (CAS 1076198-61-2)
- 6-(3-Hydroxypropyl)benzo[c][1,2]oxaborol-1(3H)-ol (CAS 1268390-57-3)
- 2-(4-Ethoxy-3-methoxyphenyl)ethan-1-ol (CAS 77891-29-3)
- Ethyl 1-(4-bromophenyl)-5-fluoro-1H-pyrazole-4-carboxylate (CAS 1269293-78-8)
- 4,5-Dichloro-6-(1-piperidinyl)pyrimidine (CAS 1823346-49-1)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
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