Cyclobutane-1,1,3,3-tetracarboxylic acid CAS 7371-69-9
| CAS No. | 7371-69-9 |
| Molecular Formula | C8H8O8 |
| Molecular Weight | 232.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cyclobutane-1,1,3,3-tetracarboxylic acid.
Cyclobutane-1,1,3,3-tetracarboxylic acid (CAS 7371-69-9), molecular formula C8H8O8 and molecular weight 232.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Cyclobutane-1,1,3,3-tetracarboxylic acid (C8H8O8) is characterized by a carbohydrate-derived structure. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Cyclobutane-1,1,3,3-tetracarboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8O8 |
| Molecular Weight | 232.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Cyclobutane Standards
- 2-Oxo-cyclobutane Undecanoic Acid (CAS 169263-77-8)
- [1,1'-bi(cyclobutane)]-1,1'-dicarboxylic acid (CAS 99173-29-2)
- 1,2,3,4-cyclobutane tetracarboxylic dianhydride 1,2,3,4-cyclobutanetetracarboxylic acid dianhydride; 1,2,3,4-cyclobutanetetracarboxylic dianhydride; 1,2,3,4-cyclobutantetracarboxylic acid dianhydride; 4415-87-6 EBD217581 cyclobutane tetracarboxylic dianhydride; cyclobutane-1,2,3,4-tetracarboxylic dianhydride cyclobutane-1,2,3,4-tetracarboxylic dianhydride; cyclobutanetetracarboxylic dianhydride; (CAS 4415-87-6)
- Cyclobutane-1,1,2-tricarboxylic acid (CAS 2144-31-2)
- [1,1'-Bi(cyclobutane)]-1-carboxylic acid (CAS 1603551-47-8)
- [1,1'-Bi(cyclobutane)]-3-carboxylic acid (CAS 76731-21-0)
- trans-cyclobutane-1,2-dicarboxylic acid (CAS 1124-13-6)
- Cis-cyclobutane-1,2-dicarboxylic acid (CAS 1461-94-5)
Recommended Standards
- Binimetinib Impurity 1 (CAS 284030-58-6)
- n-((5-Bromothiophen-2-yl)methyl)prop-2-en-1-amine (CAS 851452-55-6)
- 5-Bromo-2-(isopropylthio)pyridine (CAS 98626-93-8)
- rel-(1R,2R,3S,4S)-Cyclobutane-1,2,3,4-tetracarboxylic acid (CAS 38841-00-8)
- Methyl (2S,3S)-3-hydroxypiperidine-2-carboxylate hydrochloride (CAS 2306252-69-5)
- 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (CAS 99087-42-0)
- 4,4-Dimethyl-pyrrolidine-2-carboxylic acid ethyl ester tosylate (CAS 1965308-73-9)
- 3-(5-amino-1,3,4-thiadiaZol-2-yl)benzonitrile (CAS 1019575-49-5)
- Diethyl 2,5-Dioxahexanedioate (CAS 35466-87-6)
- 1-(6-(4-Ethylpiperazin-1-yl)-4-methylpyridin-3-yl)ethan-1-amine (CAS 1355237-36-3)
- 2-amino-thiophene-3-carboxylic acid amide (CAS 14080-51-4)
- 5-{[(E)-(4-Fluorophenyl)methylidene]amino}-6-imino-2-oxo-1-phenyl-1,2,3,6-tetrahydro-4-pyrimidinecarbonitrile (CAS 937604-56-3)
- Olaparib Impurity 127 (CAS CATO-C4X-1135127)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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