Olaparib Impurity 127 CAS CATO-C4X-1135127
| CAS No. | CATO-C4X-1135127 |
| Molecular Formula | C24H23FN4O3 |
| Molecular Weight | 434.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Olaparib Impurity 127 (C24H23FN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Olaparib Impurity 127 (CAS CATO-C4X-1135127), a pharmacopoeial impurity reference standard (molecular formula C24H23FN4O3, MW 434.46 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Olaparib Impurity 127 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23FN4O3 |
| Molecular Weight | 434.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib (CAS 763113-22-0)
- Olaparib Impurity 122 (CAS CATO-C4X-1135122)
- Olaparib Impurity 123 (CAS CATO-C4X-1135123)
- Olaparib Impurity 124 (CAS CATO-C4X-1135124)
- Olaparib Impurity 125 (CAS CATO-C4X-1135125)
- Olaparib Impurity 126 (CAS CATO-C4X-1135126)
- Olaparib Impurity 8 (CAS CATO-C4X-11358)
- Olaparib Impurity 116 (CAS CATO-C4X-1135116)
Recommended Standards
- Sivelestat (CAS 127373-66-4)
- Sivelestat Impurity 6 (CAS CATO-C4X-21236)
- Evocalcet impurity 55 (CAS CATO-C4X-248555)
- N-(2,6-dimethylpyrimidin-4-yl)-4-(((3-hydroxy-1-oxo-1H-inden-2-yl)methylene)amino)benzenesulfonamide (CAS 1024128-19-5)
- Mirogabalin Impurity 139 (CAS 193813-71-7)
- Crizotinib Impurity 67 (CAS CATO-C4X-102567)
- Parecoxib Impurity 51 (CAS 2304623-35-4)
- n-Cyclopentyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 1023454-63-8)
- 2-Methoxy-N-(2-methylbutyl)pyridin-3-amine (CAS 1157628-75-5)
- 1h-Indole-6-carbothioamide (CAS 885272-19-5)
- 4-((1H-Imidazol-1-yl)methyl)phenol (CAS 41833-17-4)
- 3-Amino-N-hydroxypropanamide (CAS 36212-73-4)
- 1-(2-Isobutoxyphenyl)-N-methylmethanamine hydrochloride (CAS 1609402-94-9)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com