N-(2,5-Difluorophenyl)-4-nitrobenzenesulfonamide CAS 738-46-5
| CAS No. | 738-46-5 |
| Molecular Formula | C12H8F2N2O4S |
| Molecular Weight | 314.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(2,5-Difluorophenyl)-4-nitrobenzenesulfonamide (C12H8F2N2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies N-(2,5-Difluorophenyl)-4-nitrobenzenesulfonamide (CAS 738-46-5), a certified reference material (molecular formula C12H8F2N2O4S, MW 314.26 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2,5-Difluorophenyl)-4-nitrobenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F2N2O4S |
| Molecular Weight | 314.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(2,6-Difluorophenyl)-3-nitrobenzenesulfonamide (CAS 1023805-47-1)
- N-(2,4-Difluorophenyl)-4-nitrobenzenesulfonamide (CAS 737-04-2)
- N-(3,5-Difluorophenyl)-4-nitrobenzenesulfonamide (CAS 738-67-0)
- N-(2,4-difluorophenyl)-N'-methyl-3-(trifluoromethyl)benzimidamide (CAS 303149-01-1)
- 4-((2,4-Difluorophenyl)amino)-2-morpholino-4-oxobutanoic acid (CAS 941921-42-2)
- Methyl 1-(2,4-Difluorophenyl)-3-phenyl-1H-pyrazole-5-carboxylate (CAS 1202030-37-2)
- 1-(2,4-Difluorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-79-6)
- 1-(2,4-Difluorophenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-18-4)
Recommended Standards
- Ethyl 5-Methyl-2-[4-(trifluoromethoxy)phenyl]-1H-imidazole-4-carboxylate (CAS 868851-35-8)
- Ensitrelvir Impurity 8 (CAS CATO-C4X-25198)
- Ethyl 1-(2-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 948293-79-6)
- Pretomanid Impurity 26 (CAS 1131005-00-9)
- 3-[4-(tert-Butyl)phenoxy]pyrrolidine hydrochloride (CAS 1185297-35-1)
- 3-Amino-4-(4-(4-fluorophenyl)piperazin-1-yl)benzamide (CAS 1706450-61-4)
- 3-(4-Fluorophenyl)bicyclo[1.1.1]pentan-1-amine hydrobromide (CAS 2306270-96-0)
- Terbium(III) carbonate (CAS 6067-34-1)
- 2-Isoxazol-3-yl-phenol (CAS 61348-48-9)
- Methyl 3-(((benzyloxy)carbonyl)(methyl)amino)propanoate (CAS 109141-51-7)
- 2-Amino-4H-cyclopenta[d]thiazol-6(5H)-one (CAS 1026710-03-1)
- 5,6-dichloro-1,2-dihydroquinazolin-2-one (CAS 67092-17-5)
- 3-(1H-Indol-3-yl)-2-mercaptopropanoic acid (CAS 27266-99-5)
- Peptide 440 (CAS CATO-CPTD788440)
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