Ranitidine EP Impurity C CAS 73851-70-4
| CAS No. | 73851-70-4 |
| Molecular Formula | C13H22N4O4S |
| Molecular Weight | 330.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ranitidine EP Impurity C (CAS 73851-70-4, C13H22N4O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ranitidine EP Impurity C (C13H22N4O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H22N4O4S |
| Molecular Weight | 330.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ranitidine Standards
- Ranitidine EP Impurity E (CAS 73857-20-2)
- Ranitidine Impurity 28 (CAS CATO-C4X-137028)
- Ranitidine Impurity 1 (CAS 72115-14-1)
- Ranitidine-D6 (CAS 1185514-83-3)
- Ranitidine N,S-Dioxide (CAS 1185237-42-6)
- Ranitidine (CAS 66357-35-5)
- Ranitidine EP Impurity D (CAS 117846-02-3)
- Ranitidine Impurity 22 (CAS CATO-C4X-137022)
Recommended Standards
- Febuxostat Impurity 88 (CAS 144060-84-4)
- Febuxostat Impurity 77 (CAS CATO-C4X-116277)
- Pimavanserin Impurity 12 (CAS CATO-C4X-193812)
- Febuxostat Impurity 71 (CAS 923942-34-1)
- Pimavanserin Impurity 50 (CAS CATO-C4X-193850)
- Fluconazole Impurity 75 (CAS CATO-C4X-101975)
- Sarpogrelate Impurity 47 (CAS CATO-C4X-291347)
- 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine (CAS 71257-38-0)
- Boc-PEG4-acid (CAS 2244684-38-4)
- 5-Methyl-6-phenylpyrimidine-2,4(1H,3H)-dione (CAS 25796-67-2)
- Leucogen Impurity 15 (CAS CATO-C4X-288915)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 477332-70-0)
- N1-(2,4,6-trimethylbenzyl)ethane-1,2-diamine (CAS 676473-67-9)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
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