Alendronic Acid Impurity 3 CAS 73858-59-0

Description

Compared with other compounds in its class, the molecular weight of 151.10 g/mol gives Alendronic Acid Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Alendronic Acid Impurity 3 (CAS 73858-59-0, C4H10NO3P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Structurally, Alendronic Acid Impurity 3 (C4H10NO3P) contains an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 0.5, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 151.10 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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